Today's Lancet is a special issue on diabetes, published to coincide with the 70th Scientific Sessions meeting of the American Diabetes Association (ADA) in Orlando, Florida on June 26—29.

Four Articles add precision to cardiovascular risk in people with type 2 diabetes, or describe new strategies in pharmacological pathways, dosing, and delivery.

But there is a glaring absence: no research on lifestyle interventions to prevent or reverse diabetes. In this respect, medicine might be winning the battle of glucose control, but is losing the war against diabetes. Since 2000, the number of people with diabetes has more than doubled to 285 million.

Increasing evidence suggests that glucocentric treatment might not result in better overall outcomes.

To help Americans make better choices more easily, the US Department of Agriculture released updated dietary guidelines on June 15 that aim to shift consumption towards more plant-based foods.

By contrast, on the same day in Brussels (and amid intense lobbying by multinational food corporations), the European Parliament rejected plans to aid consumers by labelling food with a health traffic-light system.

The ADA meeting offers world leaders in diabetes an opportunity to reflect on the above challenges and initiate debate on a more inclusive and effective strategy to control diabetes.

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Se artiklarna publicerade i the Lancet idag online
More insights on the dysglycaemia–cardiovascular connection

Hertzel C Gerstein
Full Text | PDF
Dapagliflozin, an SGLT2 inhibitor, for diabetes

Markolf Hanefeld, Thomas Forst
Full Text | PDF
Longacting exenatide in diabetes: DURATION-3

Anoop Misra, Shashank Joshi
Full Text | PDF
Inhaled insulin: new formulation, new trial

Clifford J Bailey, Anthony H Barnett
Full Text | PDF
Linking diabetes and cancer: a consensus on complexity

Andrew Renehan, Ulf Smith, M Sue Kirkman
Full Text | PDF
Gridlocked guidelines for diabetes

Richard Kahn, Edwin A M Gale
Full Text | PDF
Social determinants of diabetes and challenges of prevention

Nigel Unwin, David Whiting, Gojka Roglic
Full Text | PDF
Issue Articles
Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies

The Emerging Risk Factors Collaboration
Summary | Full Text | PDF
Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial

Clifford J Bailey, Jorge L Gross, Anne Pieters, Arnaud Bastien, James F List
Summary | Full Text | PDF
Once weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes (DURATION-3): an open-label randomised trial

Michaela Diamant, Luc Van Gaal, Stephen Stranks, Justin Northrup, Dachuang Cao, Kristin Taylor, Michael Trautmann
Summary | Full Text | PDF
Prandial inhaled insulin plus basal insulin glargine versus twice daily biaspart insulin for type 2 diabetes: a multicentre randomised trial

Julio Rosenstock, Daniel L Lorber, Luigi Gnudi, Campbell P Howard, David W Bilheimer, P-C Chang, Richard E Petrucci, Anders H Boss, Peter C Richardson
Summary | Full Text | PDF
Issue Seminars
Diabetes in sub-Saharan Africa

Jean Claude N Mbanya, Ayesha A Motala, Eugene Sobngwi, Felix K Assah, Sostanie T Enoru
Summary | Full Text | PDF
Lipid-induced insulin resistance: unravelling the mechanism

Varman T Samuel, Kitt Falk Petersen, Gerald I Shulman
Summary | Full Text | PDF
Return to Series page

Audio
Listen to a summary of the issue, including an author interview about a new therapeutic approach to type 2 diabetes treatment.
(mp3, 16:19 mins, 14.9Mb)
Related Articles published in The Lancet
Type 2 diabetes—time to change our approach

The Lancet
Full Text | PDF
Asia-Pacific faces diabetes challenge

Margaret Harris Cheng
Full Text | PDF
The challenge of childhood obesity and diabetes

Martin Silink
Full Text | PDF
Juliana Chan—helping patients live with diabetes

Margaret Harris Cheng
Full Text | PDF
Anti-TNFá therapy—killing two birds with one stone?

Sefina Arif, Patricia Cox, Behdad Afzali, Giovanna Lombardi, Robert I Lechler, Mark Peakman, Vincenzo Mirenda
Full Text | PDF
Diabetic retinopathy

Ning Cheung, Paul Mitchell, Tien Yin Wong
Summary | Full Text | PDF
Vitamins C and E for prevention of pre-eclampsia in women with type 1 diabetes (DAPIT): a randomised placebo-controlled trial

David R McCance, Valerie A Holmes, Michael J A Maresh, Christopher C Patterson, James D Walker, Donald W M Pearson, Ian S Young
Summary | Full Text | PDF
Vitamin C and E to prevent pre-eclampsia in diabetic women

Baha M Sibai
Full Text | PDF
Efficacy and safety of exenatide once weekly versus sitagliptin or pioglitazone as an adjunct to metformin for treatment of type 2 diabetes (DURATION-2): a randomised trial

Richard M Bergenstal, Carol Wysham, Leigh MacConell, Jaret Malloy, Brandon Walsh, Ping Yan, Ken Wilhelm, Jim Malone, Lisa E Porter
Summary | Full Text | PDF
Individualised incretin-based treatment for type 2 diabetes

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